Already, the country has slammed a curfew and closed all land, sea, rail and air links.
Foreign Minister Alpha Barry is among the four ministers declared positive in a day.
He initially dismissed the news as rumour. But hours later, in a post on Twitter, he admitted contracting the deadly virus.
“The rumour has become reality … I have just been notified positive for COVID-19”, he wrote, without revealing more information about his condition.
Barry was the third minister declared infected by COVID-19 in a single day.
The country’s education minister, Stanislas Ouaro, and that of mines, Oumaru Idani, also tested positive on Friday.
Also reported positive was minister of territorial administration Simeon Sawadogo.
“I wish to inform the public opinion that I have been tested positive at #Covid19.
Consequently I invite all my collaborators as well as all the people having been in contact with me to kindly report themselves to the competent services by calling 3535”, Sawadogo tweeted.
Roch Marc Christian Kabore, President of Burkina Faso, on Friday evening announced a curfew throughout the country from 7 p.m. to 5 a.m., and the closure of land, air and rail borders.
These measures will become effective from midnight March 21.